Deep Learning-Based Transaminase Catalytic Performance and Stereoselectivity Prediction System
A fixed-deployment AI platform using deep feature fusion to predict apparent catalytic efficiency, high stereoselectivity and major product configuration of transaminase candidates.
Complete health response
Catalytic performance
The 3437-dimensional catalytic feature set is fused into a 192-dimensional latent representation before family-aware regression. The server reports log10(kcat_app) and kcat_app.
High stereoselectivity
The 2051-dimensional stereochemical feature set is fused into a 304-dimensional latent representation. The fixed classifier reports the probability that ee reaches at least 99.8%.
Major configuration
The fixed configuration module uses the same 304-dimensional fused representation and reports the predicted R/S class, together with P(R) and P(S).
Applicability
Predictions are most reliable for enzyme families, substrates, mutation patterns and reaction conditions represented by the training distribution. Experimental verification remains required.